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Selected Publications

Sugimoto S, Mena HA, Sansbury BE, Kobayashi S, Tsuji T, Wang CH, Yin X, Huang TL, Kusuyama J, Kodak SD, Darcy J, Profeta G, Pereira N, Tanzi RE, Zhang C, Serwold T, Kokkotou E, Goodyear LJ, Cypess AM, Leiria LO, Spite M*, Tseng YH.  Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation. (2022) Nature Metabolism 4:775-79 *Co-corresponding author

Sansbury BE, Li X, Wong B, Patsalos A, Giannakis N, Zhang MJ, Nagy L, Spite M.  Myeloid ALX/FPR2 regulates vascularization following tissue injury. (2020) Proc. Natl. Acad. Sci. U.S.A. 117:14354-14364

Giannakis N, Sansbury BE, Patsalos A, Hays TT, Riley CO, Han X, Spite M*, Nagy L Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration. (2019) Nature Immunology 20:765-767. *Co-corresponding author (See video highlight below)

Zhang MJ, Sansbury BE, Hellmann J, Baker JF, Guo L, Parmer CM, Prenner JC, Conklin DJ, Bhatnagar A, Creager MA, Spite M Resolvin D2 enhances post-ischemic revascularization while resolving inflammation. (2016) Circulation 134:666-80.

Sansbury BE, Spite M. Resolution of acute inflammation and the role of resolvins in immunity, thrombosis and vascular biology. (2016) Circulation Research 119:113-30

Varga T, Mounier R, Patsalos A, Gogolak P, Peloquing M, Horvath A, Pap A, Daniel B, Nagy G, Pintye E, Poliska S, Cuvellier S, Larbi SB, Alvarado G, Sansbury BE, Spite M, Brown CW, Chazaud B, Nagy L. PPARγ in repair macrophages controls GDF3 and skeletal muscle regeneration. (2016)  Immunity 45:1038-1051

Fredman G, Hellmann J, Proto J, Kuriakose G, Colas R, Dorweiler B, Connolly E, Solomon R, Heyer E, Jones D, Spite M*, Tabas I. An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques. (2016) Nature Communications 7:12859.  *Co-corresponding author

Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I MerTK cleavage limits pro-resolving mediator biosynthesis and exacerbates tissue inflammation. (2016) Proc. Natl. Acad. Sci. 113:6526-31.

Spite M, Claria J, Serhan CN Resolvins, specialized pro-resolving lipid mediators and their potential roles in metabolic diseases. (2013) Cell Metabolism 19: 21-36

Tang Y, Zhang MJ, Hellmann J, Kosuri M, Bhatnagar A, Spite M Pro-resolving therapy for the treatment of delayed healing of diabetic wounds. (2013)  Diabetes  62:618-27.

Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M, Serhan CN. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. (2009) Nature  461:1287-1291.

Serhan CN, Yang R, Martinod K, Kasuga K, Pillai PS, Porter TF, Oh SF, Spite M. Maresins: novel macrophage mediators with potent anti-inflammatory and pro-resolving actions. (2009) Journal of Experimental Medicine. 206: 15-23.

See all Publications

Dynamic changes to lipid mediators support transitions among macrophages during muscle regeneration

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